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Nitroglycerin increases cGMP which activates protein kinase G which is responsible for K+ channel activation and Ca++ channel block. As a result intracellular Ca++ decreased that relaxes vascular smooth muscle, so oxygen enriched blood flow to myocardium increased and give relief from anginal pain.


Angina pectoris (maintenance therapy).
Dosage & Administration: 

1-2 tablet 2-3 times daily.

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