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Kdrin
Procyclidine
Description:
Procyclidine (Kdrin) is a synthetic antispasmodic compound. It has been shown to be useful for the treatment of parkinsonism including post encephalitic, arteriosclerotic and idiopathic types. Procyclidine successfully relieves the symptoms of extrapyramidal dysfunction (e.g. dystonia, akathisia and dyskinesia) which accompany the therapy of mental disorder with phenothiazine or other drugs.
Procyclidine (Kdrin) is a synthetic antispasmodic compound. It has been shown to be useful for the treatment of parkinsonism including post encephalitic, arteriosclerotic and idiopathic types. Procyclidine successfully relieves the symptoms of extrapyramidal dysfunction (e.g. dystonia, akathisia and dyskinesia) which accompany the therapy of mental disorder with phenothiazine or other drugs.
Indications:
Extrapyramidal symptoms, e.g. pseudoparkinsonism, acute dystonic reactions, akathisia. Symptoms induced by neuroleptic drugs. All forms of parkinsons disease, e.g. idiopathic parkinsonism, post-encephalitic parkinsonism, arteriosclerotic parkinsonism.
Extrapyramidal symptoms, e.g. pseudoparkinsonism, acute dystonic reactions, akathisia. Symptoms induced by neuroleptic drugs. All forms of parkinsons disease, e.g. idiopathic parkinsonism, post-encephalitic parkinsonism, arteriosclerotic parkinsonism.
Mode of Action:
Procyclidine is a competitive inhibitor of the peripheral actions of acetylcholine at muscarinic sites. It antagonizes the effects associated with stimulations of central receptors such as nicotine induced tremor.
Procyclidine is a competitive inhibitor of the peripheral actions of acetylcholine at muscarinic sites. It antagonizes the effects associated with stimulations of central receptors such as nicotine induced tremor.
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