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Met
Metformin Hydrochloride
Description:
Metformin Hydrochloride (Met”) is an oral biguanide antidiabetic. Metformin reduces elevated blood glucose concentration in patients with diabetes, but it does not increase insulin secretion. It exerts blood glucose lowering effects through the augmentation of muscular glucose uptake and utilization and reduction of increased hepatic glucose production. Metformin potentiates insulin action mainly by a post-receptor mechanism. In this way, metformin ameliorates insulin resistance.
Metformin Hydrochloride (Met”) is an oral biguanide antidiabetic. Metformin reduces elevated blood glucose concentration in patients with diabetes, but it does not increase insulin secretion. It exerts blood glucose lowering effects through the augmentation of muscular glucose uptake and utilization and reduction of increased hepatic glucose production. Metformin potentiates insulin action mainly by a post-receptor mechanism. In this way, metformin ameliorates insulin resistance.
Indications:
Type 2 diabetes (non-insulin dependent diabetes); type 1 diabetes (insulin dependent diabetes) as adjuvant therapy in combination with insulin; obesity and insulin resistance; hyperlipoproteinemia.
Type 2 diabetes (non-insulin dependent diabetes); type 1 diabetes (insulin dependent diabetes) as adjuvant therapy in combination with insulin; obesity and insulin resistance; hyperlipoproteinemia.
Mode of Action:
Metformin Hydrochloride (Met”) decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Metformin Hydrochloride (Met”) decreases hepatic glucose production, decreases intestinal absorption of glucose and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
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