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Prucalo
Prucalopride
Description:
Prucalopride is a selective serotonin type 4 (5-HT4) receptor agonist which is used to treat impaired motility associated with chronic constipation, thus normalizing bowel movements. Prucalopride shows no interaction with 5-HT1 receptors which reduces significantly the cardiovascular risk found in other similar drugs.
Prucalopride is a selective serotonin type 4 (5-HT4) receptor agonist which is used to treat impaired motility associated with chronic constipation, thus normalizing bowel movements. Prucalopride shows no interaction with 5-HT1 receptors which reduces significantly the cardiovascular risk found in other similar drugs.
Indications:
Prucalo® is indicated for symptomatic treatment of chronic constipation in adults in whom laxatives fail to provide adequate relief.
Prucalo® is indicated for symptomatic treatment of chronic constipation in adults in whom laxatives fail to provide adequate relief.
Mode of Action:
Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation.
Prucalopride alters colonic motility patterns via serotonin 5-HT4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation.
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