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Lamo
Lamotrigine
Description:
Lamotrigine is a phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar disorder.
Lamotrigine is a phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar disorder.
Indications:
Lamotrigine is an antiepileptic drug (AED) indicated for:
Epilepsy - adjunctive therapy in patients aged 2 years and older:
Lamotrigine is an antiepileptic drug (AED) indicated for:
Epilepsy - adjunctive therapy in patients aged 2 years and older:
- Partial-onset seizures
- Primary generalized tonic-clonic seizures
- Generalized seizures of Lennox-Gastaut syndrome
Mode of Action:
Lamotrigine controls epileptic seizures by inhibiting voltage-sensitive sodium channels, thereby stabilizes neuronal membranes and consequently inhibits presynaptic excitatory neurotransmitter (e.g., glutamate and aspartate) release.
Lamotrigine controls epileptic seizures by inhibiting voltage-sensitive sodium channels, thereby stabilizes neuronal membranes and consequently inhibits presynaptic excitatory neurotransmitter (e.g., glutamate and aspartate) release.
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