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Orthoflex

Tart cherry + Curcuminoids + Boswellia serrata

Description:
Tart cherry: Tart cherry is an indigenous plant of North America. Major active constituents of Tart cherry are anthocyanins mainly cyanidin-3 -glucosylrutinoside and cyanidin-3- rutinoside. Tart cherry inhibits xanthine oxidase so that monosodium crystal is not formed in the joints and also reduces the extraction of urate from the kidney. It suppresses the expression of inflammatory markers and also cyclooxygenase enzymes. It also has the capacity to scavenge free radicals. Tart cherry is widely used for the treatment of gout, muscle pain and stiffness, joint pain, and inflammation due to osteoarthritis and also peripheral neuropathy. It also contains an adequate amount of natural melatonin that maintains the normal sleep cycle by binding with the pineal gland. It is also used to maintain a healthy cholesterol level. Curcuma longa: Modern cellular studies on Curcuminoids (extract of Curcuma longa) with almost 4000 pre-clinical investigations, prove it as one of the best studied natural products of the whole biomedical literature. Curcuminoids is known as a master switch of addressing the natural inflammatory response function by down regulating the expression of a series of cytokines, enzymes and transcription factors. Curcuminoids significantly reduces the expression of COX-2, TNF-?, IL-1?, IL-1RN and IL-6. It inhibits the formation of prostaglandin. Curcuminoids also has anti-oxidative, anti-tumoral, anti-microbial and choleretic action. Boswellia serrata: This plant extract promotes joint health by inhibiting inflammatory factors such as the 5-lipoxygenase (5-LOX) enzyme and leukotriene B4, which affect aging joints. Extracts of Boswellia serrata have been clinically studied for osteoarthritis and joint function, particularly for osteoarthritis of the knee. Boswellia may also help reduce cartilage damage in arthritis. In a placebo-controlled clinical study, Boswellia extract improved signs of joint discomfort in just 8 weeks. Boswellia serrata as a promising alternative to NSAIDs.
Indications:
Orthoflex is indicated in- . Gout . Chronic hyperuricemia . Arthritis . Exercise induced pain . Muscle damage . Joint Inflammation & pain and Muscle soreness.
Mode of Action:
There have been no reports of significant drug Interactions of Tart cherry, Curcuma longa & Boswellia serrata. But in case of Curcuma longa & Boswellia serrata there are a chance of drug interaction with blood thinner medications (e,g warfarin, heparin).
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